Basic Information
LncRNA/CircRNA Name | SNHG5 |
Synonyms | SNHG5, C6orf160, LINC00044, NCRNA00044, U50HG, bA33E24.2 |
Region | GRCh38_6:85660950-85678736 |
Ensemble | ENSG00000203875 |
Refseq | NR_003038 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | apoptosis | Drug | ||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | bladder cancer |
ICD-0-3 | C67 |
Methods | qPCR, Western blot, in vitro knockdown |
Sample | BC tissues, Bladder cancer cell lines (SW780, UMUC3, 5637, T-24) |
Expression Pattern | up-regulated |
Function Description | SNGH5 was found upregulated in BC tissues and cell lines and a high level of SNGH5 was correlated with a poor prognosis. Silencing SNHG5 inhibited the proliferation ability of BC cells and such a function was attributed to its influence on cells cycle and apoptosis. |
Pubmed ID | 29434891 |
Year | 2017 |
Title | lncRNA SNHG5 is associated with poor prognosis of bladder cancer and promotes bladder cancer cell proliferation through targeting p27. |
External Links
Links for SNHG5 | GenBank HGNC NONCODE |
Links for bladder cancer | OMIM COSMIC |