Basic Information
| LncRNA/CircRNA Name | SNHG5 |
| Synonyms | NA |
| Region | GRCh38_6:85660950-85678736 |
| Ensemble | ENSG00000203875 |
| Refseq | NR_003038 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR, Western blot etc |
| Sample | HCC specimens and the matched adjacent non-tumor tissues,cell lines (Hep3B, Huh7,THLE-2) |
| Expression Pattern | up-regulated |
| Function Description | The expression of SNHG5 and RNF38 was elevated in HCC tissues and cell lines, and highly expressed SNHG5 and RNF38 could induce apoptosis and repress proliferation, migration, as well as invasion in HCC cells. |
| Pubmed ID | 32329834 |
| Year | 2020 |
| Title | Long non-coding RNA SNHG5 promotes human hepatocellular carcinoma progression by regulating miR-363-3p/RNF38 axis. |
External Links
| Links for SNHG5 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |