Basic Information
| LncRNA/CircRNA Name | SNHG3 |
| Synonyms | NA |
| Region | GRCh38_1:28505980-28510892 |
| Ensemble | ENSG00000242125 |
| Refseq | NR_002909.1 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, RIP |
| Sample | glioma tissue, cell lines (A172, U251, U87, SHG44, HEB) |
| Expression Pattern | up-regulated |
| Function Description | It was revealed that SNHG3 was much more enriched in glioma tissues and cell lines than in normal ones. gain- or loss-of-function experiments indicated that the up-regulation of SNHG3 promoted cell proliferation, accelerate cell cycle progress, and repressed cell apoptosis. |
| Pubmed ID | 30042166 |
| Year | 2018 |
| Title | LncRNA SNHG3 Enhances the Malignant Progress of Glioma Through Silencing KLF2 and p21. |
External Links
| Links for SNHG3 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |