Basic Information
| LncRNA/CircRNA Name | C21orF96 |
| Synonyms | RUNX1-IT1, C21orf96 |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | Microarray, qPCR etc. |
| Sample | cell lines (MKN-45, MKN-28, SGC-7901, GES-1) |
| Expression Pattern | up-regulated |
| Function Description | Our results found that the expression level of C21orF96 was over-expressed in positive lymph node tissues and gastric cancer tissues. We evaluated the altered expressions of C21orF96 in gastric cancer tissues comparing to adjacent normal specimens, and their association with clinicopathological factors. We showed that the expression levels of C21orF96 were associated with gross appearance, lymphatic metastasis and distal metastasis. We also found that C21orF96 promoted the tubular formation, migration and invasion. |
| Pubmed ID | 26567621 |
| Year | 2016 |
| Title | Long Noncoding RNA C21orF96 Promotes the Migration, Invasion and Lymph Node Metastasis in Gastric Cancer. |
External Links
| Links for C21orF96 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |