Basic Information
| LncRNA/CircRNA Name | SNHG3 |
| Synonyms | NA |
| Region | GRCh38_1:28505980-28510892 |
| Ensemble | ENSG00000242125 |
| Refseq | NR_002909.1 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | Tamoxifen | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR, Western blot |
| Sample | ovarian cancer tissues, cell lines (SK-OV3, TOV-21G, and OVCAR-3) |
| Expression Pattern | up-regulated |
| Function Description | The expression levels of SNHG3 in three EOC cell lines and one control cell line, which revealed that the overall average expression levels of SNHG3 inEOC cells were significantly increased relative to control cell IOSE80. SNHG3 was not only related to ovarian cancer survival, but also energy metabolism. Furthermore, SNHG3 might be associated with drug resistance. |
| Pubmed ID | 29921511 |
| Year | 2018 |
| Title | The lncRNA SNHG3 Regulates Energy Metabolism of Ovarian Cancer by an Analysis of Mitochondrial Proteomes |
External Links
| Links for SNHG3 | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |