Basic Information
| LncRNA/CircRNA Name | SNHG17 |
| Synonyms | NA |
| Region | GRCh38_20:38420588-38435353 |
| Ensemble | ENSG00000196756 |
| Refseq | NR_015366 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR etc. |
| Sample | CRPC tissues, cell lines(LNCaP, C4-2, PC-3, and DU145) |
| Expression Pattern | up-regulated |
| Function Description | SNHG17 and CD51 were up-regulated in CRPC tissues and cells.SNHG17 functioned as a competing endogenous RNA (ceRNA) to up-regulate CD51 expression through competitively sponging microRNA-144 (miR-144), and CD51 was identified as a direct downstream target of miR-144 in CRPC. |
| Pubmed ID | 32351538 |
| Year | 2020 |
| Title | Long Non-coding RNA SNHG17 Promotes Cell Proliferation and Invasion in Castration-Resistant Prostate Cancer by Targeting the miR-144/CD51 Axis |
External Links
| Links for SNHG17 | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |