Basic Information
| LncRNA/CircRNA Name | C17orf76-AS1 |
| Synonyms | LRRC75A-AS1, C17orf45, C17orf76-AS1, FAM211A-AS1, NCRNA00188, TSAP19 |
| Region | GRCh38_17:16438822-16478678 |
| Ensemble | ENSG00000175061 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | triple negative breast cancer |
| ICD-0-3 | C50 |
| Methods | Microarray, qPCR etc. |
| Sample | primary breast cancer tissues, cell lines (MDA-MB-231, HCC-1937, MDA-MB-468, MDA-MB-453 etc.) |
| Expression Pattern | up-regulated |
| Function Description | The qRT-PCR results showed that, compared with non-TNBC tissues, C17orf76-AS1 and CTC-338M12.3 were dominantly up-regulated in TNBC tissues; on the other hand, RP11-434D9.1, IGKV, LINC00052, BC016831, RP4-781K5.4, and LOC441242 were obviously down-regulated. |
| Pubmed ID | 26910840 |
| Year | 2016 |
| Title | LncRNAs as new biomarkers to differentiate triple negative breast cancer from non-triple negative breast cancer. |
External Links
| Links for C17orf76-AS1 | GenBank HGNC NONCODE |
| Links for triple negative breast cancer | OMIM COSMIC |