Basic Information
| LncRNA/CircRNA Name | SNHG16 |
| Synonyms | NA |
| Region | GRCh38_17:76557766-76565348 |
| Ensemble | ENSG00000163597 |
| Refseq | NR_038108 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | neuroblastoma |
| ICD-0-3 | NA |
| Methods | RT-qPCR etc. |
| Sample | NB cell line SH-SY5Y? |
| Expression Pattern | up-regulated |
| Function Description | The expression of SNHG16 was revealed to be in line with the clinical staging of NB, and high SNHG16 expression was positively associated with poor clinical outcome. Furthermore, SNHG16 silencing inhibited cell proliferation, repressed migration, and induced cell cycle arrest at the G0/G1 phase in SH-SY5Y cells. Additionally, apoptosis was undetectable in SH-SY5Y cells following SNHG16 silencing.SNHG16 regulated cell proliferation in NB through transcriptional and translational pathways. |
| Pubmed ID | 31180520 |
| Year | 2019 |
| Title | lncRNA SNHG16 is associated with proliferation and poor prognosis of pediatric neuroblastoma |
External Links
| Links for SNHG16 | GenBank HGNC NONCODE |
| Links for neuroblastoma | OMIM COSMIC |