Basic Information
| LncRNA/CircRNA Name | SNHG15 |
| Synonyms | SNHG15, C7orf40, Linc-Myo1g, MYO1GUT |
| Region | GRCh38_7:44983023-44986961 |
| Ensemble | ENSG00000232956 |
| Refseq | NR_003697 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | Microarray, qPCR etc. |
| Sample | cell lines (HCT116, RKO, HT29, HCT15, Lovo, Caco-2, SW480 and SW620) |
| Expression Pattern | up-regulated |
| Function Description | We randomly selected three lncRNAs that were significantly up-regulated in tumors compared with normal tissues according to the above RNA-Seq data analysis for experimental validation (SNHG15, MAFG-AS1 and SLCO4A1-AS1). In agreement with these findings, the q-PCR results confirmed the changes in expression patterns for the three lncRNAs in all eight CRC cell lines. |
| Pubmed ID | 27147563 |
| Year | 2016 |
| Title | Integrative analysis reveals clinical phenotypes and oncogenic potentials of long non-coding RNAs across 15 cancer types. |
External Links
| Links for SNHG15 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |