Basic Information
| LncRNA/CircRNA Name | SNHG15 |
| Synonyms | NA |
| Region | GRCh38_7:44983023-44986961 |
| Ensemble | ENSG00000232956 |
| Refseq | NR_003697 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | thyroid cancer |
| ICD-0-3 | C73.9 |
| Methods | qPCR, etc. |
| Sample | thyroid cancer tissue, human thyroid cancer cell lines including TPC1, FTC133, BCPAP, and 8505C, and a normal thyroid cell line Nthy-ori-3-1 |
| Expression Pattern | down-regulated |
| Function Description | SNHG15 expression was downregulated in thyroid cancer tissues and cells, and correlated with age, pathology classification, clinical stage, tumor size, distant metastasis, and disease free survival. The in vitro studies suggested SNHG15 overexpression suppressed cell proliferation, migration, and invasion in thyroid cancer. In summary, SNHG15 serves as tumor suppressive role in thyroid cancer. |
| Pubmed ID | 30623483 |
| Year | 2019 |
| Title | SNHG15 functions as a tumor suppressor in thyroid cancer. |
External Links
| Links for SNHG15 | GenBank HGNC NONCODE |
| Links for thyroid cancer | OMIM COSMIC |