Basic Information
| LncRNA/CircRNA Name | SNHG12 |
| Synonyms | SNHG12, ASLNC04080, C1orf79, LINC00100, NCRNA00100, PNAS-123 |
| Region | GRCh38_1:28578538-28582983 |
| Ensemble | ENSG00000197989 |
| Refseq | NR_024127 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | papillary thyroid cancer |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, in vitro knockdown etc. |
| Sample | cell lines (K1, BCPAP, TPC-1, Nthy-ori3-1), PTC tissue |
| Expression Pattern | up-regulated |
| Function Description | The SNHG12 expression is relatively high in PTC tissues and cells. In-vivo/in-vitro experiments prove that SNHG12 can promote the proliferation and metastasis of PTC cells through influencing the Wnt/B-catenin signaling pathway. |
| Pubmed ID | 29630517 |
| Year | 2018 |
| Title | LncRNA SNHG12 promotes the proliferation and metastasis of papillary thyroid carcinoma cells through regulating wnt/B-catenin signaling pathway. |
External Links
| Links for SNHG12 | GenBank HGNC NONCODE |
| Links for papillary thyroid cancer | OMIM COSMIC |