Basic Information
| LncRNA/CircRNA Name | SNHG12 |
| Synonyms | NA |
| Region | GRCh38_1:28578538-28582983 |
| Ensemble | ENSG00000197989 |
| Refseq | NR_024127 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | qPCR, Luciferase reporter assay, Western blot |
| Sample | PCa tissues,cell lines (PC3, DU145,RWPE1) |
| Expression Pattern | down-regulated |
| Function Description | the downregulation of SNHG12 and upregulation of miR-195 in the tumors formed by SNHG12-silenced DU145 cells were also confirmed by RT-qPCR analysis |
| Pubmed ID | 30945357 |
| Year | 2019 |
| Title | Long noncoding RNA SNHG12 promotes cell proliferation and activates Wnt/?-catenin signaling in prostate cancer through sponging microRNA-195. |
External Links
| Links for SNHG12 | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |