Basic Information
| LncRNA/CircRNA Name | SNHG12 |
| Synonyms | NA |
| Region | GRCh38_1:28578538-28582983 |
| Ensemble | ENSG00000197989 |
| Refseq | NR_024127 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot, Luciferase reporter assay, RIP etc |
| Sample | ESCC tissues,cell lines(EC9706, EC109, KYSE410, KYSE150, KYSE450) |
| Expression Pattern | up-regulated |
| Function Description | SNHG12 expression is upregulated in ESCC tissues and cells.SNHG12 upregulation promotes cell proliferation, migration, and EMT as well . |
| Pubmed ID | 32239639 |
| Year | 2020 |
| Title | Long Noncoding RNA SNHG12 Induces Proliferation, Migration, Epithelial-Mesenchymal Transition and Stemness of Esophageal Squamous Cell Carcinoma Cells via Post-Transcriptional Regulation of BMI1 and CTNNB1 |
External Links
| Links for SNHG12 | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |