Basic Information
| LncRNA/CircRNA Name | SNHG1 |
| Synonyms | SNHG1, LINC00057, NCRNA00057, U22HG, UHG, lncRNA16 |
| Region | GRCh38_11:62851988-62855914 |
| Ensemble | ENSG00000255717 |
| Refseq | NR_003098 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Western blot etc. |
| Sample | CRC tissues, cell lines (M5, LOVO, HCT116, SW480 and NCM460) |
| Expression Pattern | down-regulated |
| Function Description | SNHG1 expression was higher in CRC tissue lines other than the cancer adjacent tissues. down-regulated SNHG1 resulting in smaller tumor size and lighter tumor weight. down-regulated SNHG1 inhibited cell migration, proliferation and colony formation, but promoted cell apoptosis. down-regulated SNHG1 could inhibit CRC tumor genesis and SNHG1 might act as an important potential therapeutic target in CRC treatment. |
| Pubmed ID | 28759957 |
| Year | 2017 |
| Title | Down-regulated long non-coding RNA SNHG1 inhibits tumor genesis of colorectal carcinoma. |
External Links
| Links for SNHG1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |