Basic Information
| LncRNA/CircRNA Name | SNHG1 |
| Synonyms | SNHG1, LINC00057, NCRNA00057, U22HG, UHG, lncRNA16 |
| Region | GRCh38_11:62851988-62855914 |
| Ensemble | ENSG00000255717 |
| Refseq | NR_003098 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic ductal adenocarcinoma |
| ICD-0-3 | C25.3 |
| Methods | qPCR, Western blot |
| Sample | pancreatic ductal adenocarcinoma tissues, cell lines (Panc-1,BxPC-3, SW1990, HPDE6) |
| Expression Pattern | up-regulated |
| Function Description | we found that SNHG1 was highly expressed in PDAC tissues in comparison with adjacent noncancerous tissues, silencing of SNHG1 could significantly inhibit cell proliferation, promote cell apoptosis, as well as alter cell cycle progression. |
| Pubmed ID | 30087712 |
| Year | 2018 |
| Title | Long Noncoding RNA SNHG1 Promotes Cell Proliferation Through PI3K/AKT Signaling Pathway in Pancreatic Ductal Adenocarcinoma. |
External Links
| Links for SNHG1 | GenBank HGNC NONCODE |
| Links for pancreatic ductal adenocarcinoma | OMIM COSMIC |