Basic Information
| LncRNA/CircRNA Name | SNHG1 |
| Synonyms | SNHG1, LINC00057, NCRNA00057, U22HG, UHG, lncRNA16 |
| Region | GRCh38_11:62851988-62855914 |
| Ensemble | ENSG00000255717 |
| Refseq | NR_003098 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qRT-PCR , Luciferase reporter assay , Western blot etc. |
| Sample | glioma tissues ,normal brain tissues ,glioma cell lines (U87, U251, A172, T98G and LN229) ,normal human astrocyte cell line |
| Expression Pattern | up-regulated |
| Function Description | SNHG1 is overexpressed in glioma tissues and cell lines. SNHG1 promotes glioma progression in vitro and in vivo. SNHG1 functions as a sponge for miR-194, which acts as a suppressor in glioma.SNHG1 regulates PHLDA1 expression in a miR-194-dependent manner. |
| Pubmed ID | 31189920 |
| Year | 2019 |
| Title | The long non-coding RNA SNHG1 promotes glioma progression by competitively binding to miR-194 to regulate PHLDA1 expression |
External Links
| Links for SNHG1 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |