Basic Information
| LncRNA/CircRNA Name | snaR |
| Synonyms | SNAR-A1, SNAR-A53113498 |
| Region | GRCh19:47918429-47918550 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, RNAi, MTT assay etc. |
| Sample | cell lines (MDA-MB-231, MCF-7, SKBR3, T47D, BT474, BT20) |
| Expression Pattern | up-regulated |
| Function Description | LncRNA snaR was found to be up-regulated in breast cancer cells, and the cancer progression of MDA-MB-231 cells was significantly suppressed by down-regulation of snaR. Therefore, snaR knockdown has potential as a treatment modality for triple-negative breast cancer. |
| Pubmed ID | 27919948 |
| Year | 2016 |
| Title | Long Noncoding RNA snaR Regulates Proliferation, Migration and Invasion of Triple-negative Breast Cancer Cells. |
External Links
| Links for snaR | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |