Basic Information
LncRNA/CircRNA Name | snaR |
Synonyms | SNAR-A1, SNAR-A53113498 |
Region | GRCh19:47918429-47918550 |
Ensemble | NA |
Refseq | NA |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | liver cancer |
ICD-0-3 | C22.0 |
Methods | RT-qPCR, Western blotting etc. |
Sample | liver biopsies, plasma, cell lines(C33A , HEP G2,) |
Expression Pattern | up-regulated |
Function Description | The expression of snaR and TGF-?1 was significantly increased in the patients with HCC compared with the healthy controls. The plasma expression levels of snaR and TGF-?1 were positively correlated in patients with HCC; however, not in healthy controls. snaR overexpression significantly promoted cancer cell migration and invasion, and additionally increased TGF-?1 expression. |
Pubmed ID | 31186778 |
Year | 2019 |
Title | Long Non-Coding RNA snaR Is Involved in the Metastasis of Liver Cancer Possibly Through TGF-?1 |
External Links
Links for snaR | GenBank HGNC NONCODE |
Links for liver cancer | OMIM COSMIC |