Basic Information
| LncRNA/CircRNA Name | SLC2A1-AS1 |
| Synonyms | NA |
| Region | GRCh38_1:42959049-42983358 |
| Ensemble | ENSG00000227533 |
| Refseq | NR_033967 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qRT-PCR, Western blot |
| Sample | HCC tissues,Cell lines |
| Expression Pattern | down-regulated |
| Function Description | SLC2A1-AS1 exerts its regulatory role on GLUT1 by competitively binding to STAT3, and inhibits the transactivation of FOXM1 via STAT3, thus resulting in inactivation of the FOXM1/GLUT1 axis in HCC cells. |
| Pubmed ID | 32174012 |
| Year | 2020 |
| Title | Long noncoding RNA SLC2A1-AS1 regulates aerobic glycolysis and progression in hepatocellular carcinoma via inhibiting the STAT3/FOXM1/GLUT1 pathway |
External Links
| Links for SLC2A1-AS1 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |