Basic Information
| LncRNA/CircRNA Name | SIK1-lnc |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot |
| Sample | lung cancer tissues, cell lines (BEAS-2B, A549, H1975, H460) |
| Expression Pattern | down-regulated |
| Function Description | Both SIK1-LNC and SIK1 expression levels were evidently downregulated in 30 lung cancer tissues. SIK1-LNC expression was bound up with clinicopathologic features, including lymph node metastasis and distant metastasis in lung cancer cells. SIK1-LNC exerted a significant repression on cell proliferatiive, miogrative and invasive abilities of lung cancer cells. |
| Pubmed ID | 30050311 |
| Year | 2018 |
| Title | SIK1-LNC Represses the Proliferative, Migrative, and Invasive Abilities of Lung Cancer Cells. |
External Links
| Links for SIK1-lnc | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |