Basic Information
| LncRNA/CircRNA Name | SFTA1P |
| Synonyms | SFTA1P, SFTPF |
| Region | GRCh38_10:10784437-10794980 |
| Ensemble | ENSG00000225383 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung adenocarcinoma |
| ICD-0-3 | C34 |
| Methods | qPCR, Cell transfection, Cell migration and invasion assay etc. |
| Sample | LAD tissues, cell lines (A549, H1975, SPC-A1, PC9, H1299, H1650, and SK-MES-1) |
| Expression Pattern | down-regulated |
| Function Description | SFTA1P expression was down-regulated in all LUAD cell lines compared with HBE. In addition, gain-of-function studies including growth curves, migration, invasion assays, and in vivo studies were performed to verify the tumor suppressor role of SFTA1P in non-small cell lung cancer. |
| Pubmed ID | 28231733 |
| Year | 2017 |
| Title | The pseudogene-derived long noncoding RNA SFTA1P is down-regulated and suppresses cell migration and invasion in lung adenocarcinoma. |
External Links
| Links for SFTA1P | GenBank HGNC NONCODE |
| Links for lung adenocarcinoma | OMIM COSMIC |