Basic Information
| LncRNA/CircRNA Name | SDMGC |
| Synonyms | TRIM16, EBBP |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | Microarray, qPCR, Cell proliferation assay, Cell migration and invasion assay etc. |
| Sample | gastric cancer tissues, cell lines (AGS, BGC-823, HGC-27, SGC-7901, MKN-28, NCI-N87) |
| Expression Pattern | up-regulated |
| Function Description | Expression of SDMGC and TRIM16 was upregulated in the distant metastasis tissues, compared with primary GC tissues, which were positive correlation. Silencing of SDMGC or TRIM16 was demonstrated to decrease cell invasion and migration, while upregulated of SDMGC or TRIM16 could promote cell invasion and migration. |
| Pubmed ID | 25866896 |
| Year | 2015 |
| Title | Long noncoding ribonucleic acid specific for distant metastasis of gastric cancer is associated with TRIM16 expression and facilitates tumor cell invasion in vitro. |
External Links
| Links for SDMGC | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |