Basic Information
| LncRNA/CircRNA Name | SChLAP1 |
| Synonyms | SCHLAP1, LINC00913, PCAT11, PCAT114 |
| Region | GRCh38_2:180692104-180916939 |
| Ensemble | ENSG00000281131 |
| Refseq | NR_104323 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | Microarray, ISH etc. |
| Sample | prostate cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | SChLAP1 expression increases with prostate cancer progression, and high SChLAP1 expression by ISH is associated with poor outcome after radical prostatetcomy in patients. This study highlights SChLAP1 as a novel lncRNA that promotes tumor cell invasion and metastasis, and associates with lethal disease. |
| Pubmed ID | 25499224 |
| Year | 2014 |
| Title | A Novel RNA In Situ Hybridization Assay for the Long Noncoding RNA SChLAP1 Predicts Poor Clinical Outcome After Radical Prostatectomy in Clinically Localized Prostate Cancer. |
External Links
| Links for SChLAP1 | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |