Basic Information
| LncRNA/CircRNA Name | SChLAP1 |
| Synonyms | SCHLAP1, LINC00913, PCAT11, PCAT114 |
| Region | GRCh38_2:180692104-180916939 |
| Ensemble | ENSG00000281131 |
| Refseq | NR_104323 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | prostate cancer |
| ICD-0-3 | C61.9 |
| Methods | ISH etc. |
| Sample | prostate cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | Of the 937 patients evaluated, 89 (9.5%) had high SChLAP1 expression, which in patients treated with radical prostatectomy was strongly associated with development of lethal PCa independent of age, Gleason score, pathologic stage, and PTEN status. |
| Pubmed ID | 26724257 |
| Year | 2016 |
| Title | Overexpression of the Long Non-coding RNA SChLAP1 Independently Predicts Lethal Prostate Cancer. |
External Links
| Links for SChLAP1 | GenBank HGNC NONCODE |
| Links for prostate cancer | OMIM COSMIC |