Basic Information
| LncRNA/CircRNA Name | SChLAP1 |
| Synonyms | SCHLAP1, LINC00913, PCAT11, PCAT114 |
| Region | GRCh38_2:180692104-180916939 |
| Ensemble | ENSG00000281131 |
| Refseq | NR_104323 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qPCR, RNAi, Flow cytometry assay etc. |
| Sample | cell lines (T24 and 5637) |
| Expression Pattern | up-regulated |
| Function Description | SChLAP1 was overexpressed in bladder cancer tissues compared to paired normal bladder tissues. Cell growth arrest, apoptosis induction and migration inhibition were also observed in bladder cancer T24 and 5637 cells after transfection with SChLAP1 siRNA |
| Pubmed ID | 26861061 |
| Year | 2016 |
| Title | Inhibiting malignant phenotypes of the bladder cancer cells by silencing long noncoding RNA SChLAP1 |
External Links
| Links for SChLAP1 | GenBank HGNC NONCODE |
| Links for bladder cancer | OMIM COSMIC |