Basic Information
| LncRNA/CircRNA Name | SAMMSON |
| Synonyms | LINC01212 |
| Region | GRCh38_3: 69999550-70518064 |
| Ensemble | ENSG00000240405 |
| Refseq | NR_110000 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | qPCR, RIP etc. |
| Sample | cell line, liver cancer tissue |
| Expression Pattern | up-regulated |
| Function Description | Here we found long noncoding RNA SAMMSON is highly expressed in liver cancer and liver TICs. SAMMSON silenced cells show impaired self-renewal capacity, while, its overexpression induces enhanced self-renewal. |
| Pubmed ID | 29262600 |
| Year | 2017 |
| Title | SAMMSON drives the self-renewal of liver tumor initiating cells through EZH2-dependent Wnt/B-catenin activation |
External Links
| Links for SAMMSON | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |