Basic Information
| LncRNA/CircRNA Name | SAMMSON |
| Synonyms | LINC01212 |
| Region | GRCh38_3: 69999550-70518064 |
| Ensemble | ENSG00000240405 |
| Refseq | NR_110000 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | melanoma |
| ICD-0-3 | NA |
| Methods | qPCR, RIP etc. |
| Sample | cell lines (Mel501, SK-MEL-28), melanoma tissues |
| Expression Pattern | up-regulated |
| Function Description | Our results indicate that silencing of the lineage addiction oncogene SAMMSON disrupts vital mitochondrial functions in a cancer-cell-specific manner; this silencing is therefore expected to deliver highly effective and tissue-restricted antimelanoma therapeutic responses. |
| Pubmed ID | 27008969 |
| Year | 2016 |
| Title | Melanoma addiction to the long non-coding RNA SAMMSON |
External Links
| Links for SAMMSON | GenBank HGNC NONCODE |
| Links for melanoma | OMIM COSMIC |