Basic Information
| LncRNA/CircRNA Name | RUNXOR |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR |
| Sample | blood |
| Expression Pattern | up-regulated |
| Function Description | The expression of RUNXOR was higher in MDSCs isolated from the tumor tissues of lung cancer patients compared with cells from adjacent tissue. In addition, RUNXOR knockdown decreased Arg1 expression in MDSCs. we previously demonstrated that miR-9 modulates the function and development of MDSCs by targeting RUNX1 |
| Pubmed ID | 29914443 |
| Year | 2018 |
| Title | Long non-coding RNA RUNXOR accelerates MDSC-mediated immunosuppression in lung cancer. |
External Links
| Links for RUNXOR | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |