Basic Information
| LncRNA/CircRNA Name | RPPH1 |
| Synonyms | NA |
| Region | GRCh38_14:20343048-20343685 |
| Ensemble | ENSG00000277209 |
| Refseq | NR_002312 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR etc. |
| Sample | cell lines (MCF-7, MDA-MB-231) |
| Expression Pattern | up-regulated |
| Function Description | RPPH1 functions as a tumour promoter and plays an important role in advancing tumorigenesis by targeting miR-122 and may serve as a novel and potential therapeutic, diagnostic or prognostic target in breast cancer. |
| Pubmed ID | 29200969 |
| Year | 2017 |
| Title | Inhibition of breast cancer cell proliferation and tumorigenesis by long non-coding RNA RPPH1 down-regulation of miR-122 expression. |
External Links
| Links for RPPH1 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |