Basic Information
| LncRNA/CircRNA Name | RPL34-AS1 |
| Synonyms | FLJ37673, RP11-462C24.1 |
| Region | GRCh38_4:108538190-108620460 |
| Ensemble | ENSG00000234492 |
| Refseq | NR_026968 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | Microarray, qPCR etc. |
| Sample | CRC tissues |
| Expression Pattern | down-regulated |
| Function Description | We found that RP11-462C24.1 expression level was lower in cancer tissues compared with adjacent normal samples. Furthermore, its expression level was lower in CRC patients with metastasis than those without metastasis. That is, RP11-462C24.1 expression level decreased as the malignant degree of CRC increased. In addition, low expression of RP11-462C24.1 significantly correlated with more distant metastasis. |
| Pubmed ID | 24908062 |
| Year | 2014 |
| Title | Low expression of novel lncRNA RP11-462C24.1 suggests a biomarker of poor prognosis in colorectal cancer. |
External Links
| Links for RPL34-AS1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |