Basic Information
| LncRNA/CircRNA Name | RP11-600K15.1 |
| Synonyms | LINC01592 |
| Region | GRCh38_8:68911803-69104190 |
| Ensemble | ENSG00000253658 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | RIP etc. |
| Sample | esophageal cancer cell lines |
| Expression Pattern | up-regulated |
| Function Description | Here, we describe a novel lncRNA POU6F2-AS2 specifically expressed in OSCC. POU6F2-AS2 is involved in the DNA damage response and regulates cells survival after ionizing radiation. POU6F2-AS2 interacts with Ybx1 protein and regulates its chromatin localization. |
| Pubmed ID | 27033944 |
| Year | 2016 |
| Title | Long noncoding RNA POU6F2-AS2 is associated with oesophageal squamous cell carcinoma |
External Links
| Links for RP11-600K15.1 | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |