Basic Information
| LncRNA/CircRNA Name | RP11-468E2.5 |
| Synonyms | NA |
| Region | GRCh38_14:24139445-24140444 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | RT-qPCR, Western blot, RIP |
| Sample | CRC tissues,cell lines |
| Expression Pattern | down-regulated |
| Function Description | up-regulation of RP11-468E2.5 inhibits the JAK/STAT signaling pathway by targeting STAT5 and STAT6, thereby suppressing cell proliferation and promoting cell apoptosis in CRC. |
| Pubmed ID | 31718693 |
| Year | 2019 |
| Title | Long non-coding RNA RP11-468E2.5 curtails colorectal cancer cell proliferation and stimulates apoptosis via the JAK/STAT signaling pathway by targeting STAT5 and STAT6 |
External Links
| Links for RP11-468E2.5 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |