Basic Information
| LncRNA/CircRNA Name | RP11-222K16.2 |
| Synonyms | NA |
| Region | GRCh38_3:27712910-27714005 |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | acute myeloid leukemia |
| ICD-0-3 | NA |
| Methods | Microarray, qPCR |
| Sample | Bone marrow |
| Expression Pattern | differential expression |
| Function Description | RP11-222K16.2 might affect the differentiation of natural killer cells, and promote the immunized evasion of AML by regulating Eomesodermin expression. Analysis of this study revealed that dysregulated lncRNAs and mRNAs in AML vs IDA controls could affect the immune system and hematopoietic cell differentiation. |
| Pubmed ID | 29220122 |
| Year | 2018 |
| Title | Expression profile analysis of long non-coding RNA in acute myeloid leukemia by microarray and bioinformatics. |
External Links
| Links for RP11-222K16.2 | GenBank HGNC NONCODE |
| Links for acute myeloid leukemia | OMIM COSMIC |