Basic Information
| LncRNA/CircRNA Name | RP11-169D4.1-001 |
| Synonyms | RP11-169D4.2 |
| Region | GRCh38_11:72584572-72587979 |
| Ensemble | ENSG00000227467 |
| Refseq | NR_126364 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | laryngeal squamous cell cancer |
| ICD-0-3 | C32.3 |
| Methods | Microarray, qPCR etc. |
| Sample | LSCC tissues |
| Expression Pattern | up-regulated |
| Function Description | AC026166.2-001 and RP11-169D4.1-001 were distinctly dysregulated, with AC026166.2-001 exhibiting lower expression in cancer tissues and RP11-169D4.1-001 higher expression. We verified that both AC026166.2-001 and RP11-169D4.1-001 were expressed at a lower level in cervical lymph nodes compared with paired laryngeal cancer tissues and paired normal tissues. RP11-169D4.1-001 levels were positively correlated with lymph node metastasis. |
| Pubmed ID | 25243407 |
| Year | 2014 |
| Title | Long non-coding RNA profiling in laryngeal squamous cell carcinoma and its clinical significance: potential biomarkers for LSCC. |
External Links
| Links for RP11-169D4.1-001 | GenBank HGNC NONCODE |
| Links for laryngeal squamous cell cancer | OMIM COSMIC |