Basic Information
| LncRNA/CircRNA Name | ROR1-AS1 |
| Synonyms | NA |
| Region | GRCh38_1:64094442-64171297 |
| Ensemble | ENSG00000223949 |
| Refseq | NR_110665 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | nasopharyngeal cancer |
| ICD-0-3 | C11 |
| Methods | RT-qPCR, Western blot analysis, Luciferase Assays, RIP |
| Sample | tumor tissues,cell lines (5-8F, CNE2, and 618B,NP69) |
| Expression Pattern | up-regulated |
| Function Description | ROR1-AS1 could enhance NPC cell migration and invasion and induce EMT process by sponging miR-375, which suggested that ROR1-AS1/miR-375 axis may contribute to the therapy for NPC as a candidate target. |
| Pubmed ID | 31957830 |
| Year | 2020 |
| Title | Long Noncoding RNA ROR1-AS1 Induces Tumor Metastasis and Epithelial-Mesenchymal Transition by Sponging miR-375 in Nasopharyngeal Carcinoma |
External Links
| Links for ROR1-AS1 | GenBank HGNC NONCODE |
| Links for nasopharyngeal cancer | OMIM COSMIC |