Basic Information
| LncRNA/CircRNA Name | BLACAT1 |
| Synonyms | NA |
| Region | GRCh38_1:205434886-205437879 |
| Ensemble | ENSG00000281406 |
| Refseq | NR_103783 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, Luciferase reporter assay, Western blot |
| Sample | breast cancer tissues,cell lines( MCF-7, BT474, SKBR3, SUM149, MDA-MB-231, MDA-MB-435,MDA-MB-468) |
| Expression Pattern | up-regulated |
| Function Description | The present data demonstrated that lncRNA-BLACAT1 was upregulated in breast cancer, which promoted breast cancer cell proliferation and metastasis via down-regulating miR-150-5p by targeting CCR2 expression. |
| Pubmed ID | 30733855 |
| Year | 2019 |
| Title | Long non-coding RNA BLACAT1 promotes breast cancer cell proliferation and metastasis by miR-150-5p/CCR2. |
External Links
| Links for BLACAT1 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |