Basic Information
LncRNA/CircRNA Name | RNA-AWPPH |
Synonyms | NA |
Region | NA |
Ensemble | NA |
Refseq | NA |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | apoptosis | Drug | ||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | osteosarcoma |
ICD-0-3 | NA |
Methods | qRT-PCR , Western blot , in vitro knockdown etc. |
Sample | OS tissues and paracancerous tissues?,cell lines(OS MG-63 and U2OS, and the osteoblast hFOB1.19 ) |
Expression Pattern | up-regulated |
Function Description | AWPPH was highly expressed in OS tissues and cells.AWPPH depletion significantly inhibited OS cell proliferation and migration, and promoted OS cell apoptosis. AWPPH downregulation significantly inhibited the PI3K/AKT pathway. |
Pubmed ID | 31612016 |
Year | 2019 |
Title | Inhibition of Long Non-Coding RNA-AWPPH Decreases Osteosarcoma Cell Proliferation, Migration and Invasion |
External Links
Links for RNA-AWPPH | GenBank HGNC NONCODE |
Links for osteosarcoma | OMIM COSMIC |