Basic Information
| LncRNA/CircRNA Name | RMRP |
| Synonyms | RMRP, CHH, NME1, RMRPR, RRP2 |
| Region | GRCh38_9:35657751-35658018 |
| Ensemble | ENSG00000269900 |
| Refseq | NR_003051 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR etc. |
| Sample | blood |
| Expression Pattern | differential expression |
| Function Description | The panels of three miRNAs (miRs-21, 210, and 486-5p), two lncRNAs (SNHG1 and RMRP), and two FUTs (FUT8 and POFUT1) have a sensitivity of 81-86% and a specificity of 84-87% for diagnosis of lung cancer. From the seven genes, an integromic plasma signature comprising miR-210, SNHG1, and FUT8 is developed that produces higher sensitivity (95.45%) and specificity (96.97%) compared with the individual biomarker panels (all p<0.05). |
| Pubmed ID | 29872497 |
| Year | 2018 |
| Title | An integromic signature for lung cancer early detection. |
External Links
| Links for RMRP | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |