Basic Information
| LncRNA/CircRNA Name | RHPN1-AS1 |
| Synonyms | NA |
| Region | GRCh38_8:143366631-143368548 |
| Ensemble | ENSG00000254389 |
| Refseq | NR_026785 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | epithelial ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qRT-PCR, Western blot, Microarray |
| Sample | EOC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | RHPN1-AS1 promoted EOC cell proliferation and metastasis. RHPN1-AS1 acted as a ceRNA to sponge miR-596, consequently increasing LETM1 expression and activating the FAK/PI3K/Akt signaling pathway. |
| Pubmed ID | 32163372 |
| Year | 2020 |
| Title | Long non-coding RNA RHPN1-AS1 promotes tumorigenesis and metastasis of ovarian cancer by acting as a ceRNA against miR-596 and upregulating LETM1 |
External Links
| Links for RHPN1-AS1 | GenBank HGNC NONCODE |
| Links for epithelial ovarian cancer | OMIM COSMIC |