Basic Information
| LncRNA/CircRNA Name | RAMP2-AS1 |
| Synonyms | NA |
| Region | GRCh38_17:42753914-42761257 |
| Ensemble | ENSG00000197291 |
| Refseq | NR_024461 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | 2 | ||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | chondrosarcoma |
| ICD-0-3 | NA |
| Methods | Western blot , qRT-PCR, luciferase reporter assay, Microarray Analysis etc |
| Sample | Chondrosarcoma tissues and blood samples, cell line (SW1353) |
| Expression Pattern | up-regulated |
| Function Description | LncRNA microarray analysis revealed that exosomes carried lncRNA RAMP2-AS1, and further verification showed that the level of RAMP2-AS1 was increased in the serum of chondrosarcoma patients and was closely related to local invasiveness, distant metastasis and poor prognosis. |
| Pubmed ID | 32368088 |
| Year | 2020 |
| Title | Exosomal lncRNA RAMP2-AS1 Derived from Chondrosarcoma Cells Promotes Angiogenesis Through miR-2355-5p/VEGFR2 Axis. |
External Links
| Links for RAMP2-AS1 | GenBank HGNC NONCODE |
| Links for chondrosarcoma | OMIM COSMIC |