Basic Information
| LncRNA/CircRNA Name | PVT1 |
| Synonyms | PVT1, LINC00079, MYC, NCRNA00079, onco-lncRNA-100 |
| Region | GRCh38_8:127794533-128101253 |
| Ensemble | ENSG00000249859 |
| Refseq | NR_003367 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | B-cell lymphoma |
| ICD-0-3 | NA |
| Methods | qPCR, FISH, ISH etc. |
| Sample | bone marrow, lymph node, pleural effusion |
| Expression Pattern | differential expression |
| Function Description | In addition, not only MYC rearrangement but also PVT1 rearrangement may also be implicated in the disease development of HABCLs with 8q24 abnormalities. |
| Pubmed ID | 23547836 |
| Year | 2013 |
| Title | Deletion or methylation of CDKN2A/2B and PVT1 rearrangement occur frequently in highly aggressive B-cell lymphomas harboring 8q24 abnormality. |
External Links
| Links for PVT1 | GenBank HGNC NONCODE |
| Links for B-cell lymphoma | OMIM COSMIC |