Basic Information
| LncRNA/CircRNA Name | 91H |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Western blot |
| Sample | Cell lines (HCT-8, HCT-116 and FHC) |
| Expression Pattern | up-regulated |
| Function Description | serum lncRNA 91H expression was closely related to cancer exosomes in vitro and vivo which may enhance tumor-cell migration and invasion in tumor development by modifying HNRNPK expression. Then the clinic pathological significance of exosomal 91H was evaluated which demonstrated that CRC patients with high lncRNA 91H expression usually showed a higher risk in tumor recurrence and metastasis than patients with low lncRNA 91H expression (P < 0.05). |
| Pubmed ID | 29410604 |
| Year | 2018 |
| Title | Exosomal lncRNA 91H is associated with poor development in colorectal cancer by modifying HNRNPK expression. |
External Links
| Links for 91H | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |