Basic Information
| LncRNA/CircRNA Name | PURPL |
| Synonyms | NA |
| Region | GRCh38_5:27472292-27496401 |
| Ensemble | ENSG00000250337 |
| Refseq | NR_038848 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qRT-PCR , Western blot etc. |
| Sample | GC and corresponding noncancerous matched tissues |
| Expression Pattern | up-regulated |
| Function Description | Expression of PURPL was significantly upregulated in 50 GC samples . PURPL RNA level in GC was significantly related to tumor size and histopathological grade.p53 expression at both protein and mRNA levels were significantly decreased in GC tissues compared to adjacent control samples.NONHSAT062994 expression was downregulated in 50-pair GC and GC tissues from GSE13915 dataset.NONHSAT062994 was significantly associated with histological grade and tumor size. |
| Pubmed ID | 31606380 |
| Year | 2019 |
| Title | Overexpression of PURPL and Downregulation of NONHSAT062994 as Potential Biomarkers in Gastric Cancer |
External Links
| Links for PURPL | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |