Basic Information
| LncRNA/CircRNA Name | PTPRG-AS1 |
| Synonyms | PTPRG-AS1 |
| Region | GRCh38_3:62260865-62369330 |
| Ensemble | ENSG00000241472 |
| Refseq | NR_038281 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | RNA-seq, qPCR |
| Sample | breast cancer tissues |
| Expression Pattern | differential expression |
| Function Description | NKX2-1-AS1 and DSCAM-AS1, which up-regulated in the lung cancer and regulated the protein-coding genes which were associated with lung cancer. Meanwhile, the subtype breast cancer ER(+), ER(-) shared 20 different expressed lncRNAs including LINC00324, PTPRGAS1 (protein tyrosine phosphatase, receptor type, G, antisense) and SNHG17 (small nucleolar RNA host gene 20). |
| Pubmed ID | 30981459 |
| Year | 2019 |
| Title | Transcriptome sequencing profiles reveal lncRNAs may involve in breast cancer (ER/PR positive type) by interaction with RAS associated genes. |
External Links
| Links for PTPRG-AS1 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |