Basic Information
| LncRNA/CircRNA Name | BCYRN1 |
| Synonyms | NA |
| Region | NA |
| Ensemble | ENSG00000236824 |
| Refseq | NR_001568 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot |
| Sample | glioma cell lines |
| Expression Pattern | up-regulated |
| Function Description | BCYRN1 promotes glioma cell proliferation,invasion and migration in vitro. Mechanistically, upregulated expression of BCYRN1 in glioma acts as a sponge to sequester the endogenous tumor suppressor miR-125a-5p and to further increase the expression TAZ. |
| Pubmed ID | 32104095 |
| Year | 2020 |
| Title | The lncRNA BCYRN1 Functions as an Oncogene in Human Glioma by Downregulating miR-125a-5p in vitro |
External Links
| Links for BCYRN1 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |