Basic Information
| LncRNA/CircRNA Name | PRNCR1 |
| Synonyms | PRNCR1, CARLo-3, PCAT8 |
| Region | GRCh38_8:127079874-127092600 |
| Ensemble | ENSG00000282961 |
| Refseq | NR_109833 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR etc. |
| Sample | CRC tissues |
| Expression Pattern | differential expression |
| Function Description | In overall analyses, we found that the rs13252298 and rs1456315 were associated with significantly decreased risks of CRC. In stratification analyses, we found that CRC patients carrying the rs1456315G were likely to have a tumor size of greater than 5 cm (G vs. A: adjusted OR = 1.56, 95% CI: 1.10-2.23). Additionally, patients with the rs7007694C and rs16901946G had decreased risks to develop poorly differentiated CRC, whereas patients with the rs1456315G had an increased risk to develop poorly differentiated CRC. |
| Pubmed ID | 24330491 |
| Year | 2013 |
| Title | Association between polymorphisms in long non-coding RNA PRNCR1 in 8q24 and risk of colorectal cancer. |
External Links
| Links for PRNCR1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |