Basic Information
| LncRNA/CircRNA Name | PRC1-AS1 |
| Synonyms | PRC1-AS1 |
| Region | GRCh38_15:90966345-90988624 |
| Ensemble | ENSG00000258725 |
| Refseq | NR_051984 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | RNA-seq, qPCR etc. |
| Sample | cell lines (BEL-7402, HLF, HLE, HepG2, HepG2.2.15, Huh-1, Huh-7, PLC/PRF/5, Hep3B, and SK-Hep-1) |
| Expression Pattern | up-regulated |
| Function Description | All five lncRNAs were highly up-regulated in all of the cancer cell lines. PRC1- AS1, which was the lncRNA with the highest level of expression in TCGA database, was markedly upregulated in BEL7402, HepG2.2.15, Huh-1, and Hep3B; that level of expression was more than fourfold that in normal liver cell lines. |
| Pubmed ID | 27499103 |
| Year | 2016 |
| Title | Preliminary investigation of five novel long non-coding RNAs in hepatocellular carcinoma cell lines. |
External Links
| Links for PRC1-AS1 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |