Basic Information
| LncRNA/CircRNA Name | PPP3CB |
| Synonyms | PPP3CB, CALNA2, CALNB, CNA2, PP2Bbeta |
| Region | GRCh38_10:73436428-73496024 |
| Ensemble | ENSG00000107758 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | pancreatic ductal adenocarcinoma |
| ICD-0-3 | C25.3 |
| Methods | Microarray, qPCR etc. |
| Sample | cell line (MIA, PaCa-2) |
| Expression Pattern | up-regulated |
| Function Description | Statistically significant increased expression of all three intronic lncRNAs was observed. Our findings reveal sets of intronic lncRNAs expressed in pancreatic tissues whose abundance is correlated to PDAC or metastasis, thus pointing to the potential relevance of this class of transcripts in biological processes related to malignant transformation and metastasis in pancreatic cancer. |
| Pubmed ID | 22078386 |
| Year | 2011 |
| Title | Long noncoding intronic RNAs are differentially expressed in primary and metastatic pancreatic cancer. |
External Links
| Links for PPP3CB | GenBank HGNC NONCODE |
| Links for pancreatic ductal adenocarcinoma | OMIM COSMIC |