Basic Information
| LncRNA/CircRNA Name | PICART1 |
| Synonyms | RP11-1094H24.4, PICART1 |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot, etc. |
| Sample | lung cancer tissues, cell lines (A549, SPC-A-1, NCI-H358, NCI-H1975, HCI-H292, BEAS-2B) |
| Expression Pattern | down-regulated |
| Function Description | PICART1 acts as a tumor suppressor may be via regulation of JAK2/STAT3 pathway.PICART1 overexpression inhibited cell cycle progression and promoted apoptosis in SPC-A-1 and NCI-H1975 cell lines. |
| Pubmed ID | 29940776 |
| Year | 2018 |
| Title | Long non-coding RNA PICART1 suppresses proliferation and promotes apoptosis in lung cancer cells by inhibiting JAK2/STAT3 signaling. |
External Links
| Links for PICART1 | GenBank HGNC NONCODE |
| Links for lung cancer | OMIM COSMIC |