Basic Information
| LncRNA/CircRNA Name | PHBP1 |
| Synonyms | NA |
| Region | GRCh38_6:150042546-150043353 |
| Ensemble | ENSG00000213091 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal squamous cell carcinoma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot etc. |
| Sample | esophageal squamous cell carcinoma tissues, cell lines (ECa9706 and TE-1) |
| Expression Pattern | up-regulated |
| Function Description | Here, we reported that human prohibitin gene pseudogene 1 (PHBP1) was upregulated in ESCC, and increased PHBP1 expression in ESCC was associated with clinical advanced stage. |
| Pubmed ID | 28404970 |
| Year | 2017 |
| Title | Pseudogene PHBP1 promotes esophageal squamous cell carcinoma proliferation by increasing its cognate gene PHB expression |
External Links
| Links for PHBP1 | GenBank HGNC NONCODE |
| Links for esophageal squamous cell carcinoma | OMIM COSMIC |